| ID |
http://id.who.int/icd/entity/696598707 |
| Preferred Name |
maladie de Marburg |
| Definitions |
A severe disease with high case fatality caused by infection with Marburg virus or a closely related virus. Marburg disease is typically characterized by acute onset of fever with non-specific symptoms/signs (e.g., abdominal pain, anorexia, fatigue, malaise, myalgia, sore throat) usually followed several days later by nausea, vomiting, diarrhea, and occasionally a variable rash. Severe illness may include hemorrhagic manifestations (e.g., bleeding from puncture sites, ecchymoses, petechiae, visceral effusions), encephalopathy, shock/hypotension, multi-organ failure. Common laboratory findings include thrombocytopenia, elevated transaminase concentrations, electrolyte abnormalities, and signs of renal dysfunction. Individuals who recover may experience prolonged sequelae (e.g., arthralgia, neurocognitive dysfunction, uveitis), and clinical and subclinical persistent infection may occur in immune-privileged compartments (e.g., CNS, eyes, testes). Person-to-person transmission occurs by direct contact with blood, other bodily fluids, organs, or contaminated surfaces and materials with risk beginning at the onset of clinical signs and increasing with disease severity. Family members, sexual contacts, healthcare providers, and participants in burial ceremonies with direct contact with the deceased are at particular risk. The incubation period typically is 7–11 days (range ≈2–21 days). |
| Type |
http://www.w3.org/2002/07/owl#Class |
| comment | A severe disease with high case fatality caused by infection with Marburg virus or a closely related virus. Marburg disease is typically characterized by acute onset of fever with non-specific symptoms/signs (e.g., abdominal pain, anorexia, fatigue, malaise, myalgia, sore throat) usually followed several days later by nausea, vomiting, diarrhea, and occasionally a variable rash. Severe illness may include hemorrhagic manifestations (e.g., bleeding from puncture sites, ecchymoses, petechiae, visceral effusions), encephalopathy, shock/hypotension, multi-organ failure. Common laboratory findings include thrombocytopenia, elevated transaminase concentrations, electrolyte abnormalities, and signs of renal dysfunction. Individuals who recover may experience prolonged sequelae (e.g., arthralgia, neurocognitive dysfunction, uveitis), and clinical and subclinical persistent infection may occur in immune-privileged compartments (e.g., CNS, eyes, testes). Person-to-person transmission occurs by direct contact with blood, other bodily fluids, organs, or contaminated surfaces and materials with risk beginning at the onset of clinical signs and increasing with disease severity. Family members, sexual contacts, healthcare providers, and participants in burial ceremonies with direct contact with the deceased are at particular risk. The incubation period typically is 7–11 days (range ≈2–21 days). la maladie de marburg est généralement caractérisée par l'apparition aiguë de la fièvre accompagnée de symptômes / signes non spécifiques (p. ex., douleurs abdominales, anorexie, fatigue, malaise, myalgie, mal de gorge) habituellement suivie de plusieurs jours plus tard par des nausées, des vomissements, la diarrhée et parfois une éruption variable. les maladies graves peuvent comprendre des manifestations hémorragiques (p. ex., saignement des points de ponction, ecchymoses, pétéchies, effusions viscérales), encéphalopathie, état de choc / hypotension, insuffisance de plusieurs organes. les résultats courants de laboratoire comprennent la thrombocytopénie, des concentrations élevées de transaminases, des anomalies électrolytiques et des signes de dysfonction rénale. les personnes qui guérissent peuvent présenter des séquelles prolongées (p. ex. arthralgie, dysfonction neurocognitive, uv μια σοβαρή ασθένεια με υψηλό περιστατικό περίπτωση που προκαλείται από μόλυνση με τον ιό του μάρμπουργκ ή μια στενά συνδεδεμένη παρθένα. νόσος marburg χαρακτηρίζεται συνήθως από την οξεία εμφάνιση του πυρετού με μη συγκεκριμένα συμπτώματα / σημάδια (π.χ., κοιλιακό άλγος, ανορεξία, κόπωση, δυσφορία, πονόλαιμο) συνήθως ακολουθούνται αρκετές ημέρες αργότερα από nausea, έμετος, διάρροια, και κατά καιρούς μια μεταβλητή εξασθένηση. σοβαρή ασθένεια μπορεί να περιλαμβάνουν αιμορραγικές εκδηλώσεις (π.χ., αιμορραγία από τις περιοχές διάτρησης, ecchymoses, petechiae, σπλαχνική effusions), εγκεφαλοπάθεια, σοκ / υπόταση, multi-organ failure. κοινά εργαστηριακά ευρήματα περιλαμβάνουν θρομβοκυτταροπενία, αυξημένες συγκεντρώσεις transaminase, ηλεκτρολυτικές ανωμαλίες, και τα σημάδια της νεφρικής δυσλειτουργίας. άτομα που ανακάμπτουν |
| IRI | |
| icd11Chapter | 01 |
| broaderTransitive | http://id.who.int/icd/entity/1238540753 http://id.who.int/icd/entity/774338239 |
| prefLabel | maladie de Marburg |
| mms | |
| browserUrl | NA |
| narrowerTransitive | |
| icd11Code | 1D60.1Y 1D60.1Z 1D60.1 |
| label | maladie de Marburg Marburg disease marburg choroby Marburger Krankheit ασθένεια του στομάχου |
| subClassOf | http://id.who.int/icd/entity/1238540753 http://id.who.int/icd/entity/774338239 |
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